AtriCure’s AtriClip products are the most widely sold Left Atrial Appendage (LAA) management devices worldwide.
The AtriClip devices are epicardially applied to the base of the left atrial appendage (LAA) during cardiac surgery procedures such that the LAA is permanently excluded from the left atrium of the heart. This exclusion eliminates blood flow and electrical communication of blood between the left atrium (LA) and the LAA and results in the electrical isolation of the LAA from the rest of the heart.1-4
97% successful LAA exclusion5* resulting in the electrical isolation of the LAA1-4,6,7
In a published meta-analysis of over 900 clip placements, the authors observed there were no device migrations and no device related complications with more than five years follow-up.
A human clinical study found that within minutes of the epicardial application of the AtriClip Device, the LAA becomes electrically isolated from the left atrium and ischemic injury results in the cessation of electrical activity in the LAA.2 Postoperatively, the excluded and necrosed LAA is resorbed and no longer a factor in the propagation of electrical activity.3,4,6
Hallmarks of AtriClip Device Excellence
Epicardial Exclusion
- Implant is not in the blood stream
- Ischemic injury electrically isolates the LAA
- Atrophy and resorption of the LAA
Dynamic Closing Force
- Continuous closing force maintains LAA exclusion throughout changes to the tissue caused by ischemia.
Parallel / Linear Closing
- Minimized occurrence of tissue folds with optimal apposition of tissue along long axis of LAA ostia
Tissue Compression / Atraumatic
- No cutting, non-piercing, and atraumatic compression reduces risk of tissue tearing and bleeding
The AtriClip devices are available on a variety of delivery systems optimized for open concomitant procedures as well as minimally invasive surgery, both through a thoracotomy and a port.
Computed tomography (CT) before and at 3-year follow-up after AtriClip device implantation. Exemplary CT before AtriClip device placement (A and C) and after implantation depicting the AtriClip device in stable position and fully excluding the left atrial appendage at a 3-year follow up (B and D).8
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- Benussi, S. et al, Thoracoscopic Appendage Exclusion With an AtriClip Device As a Solo Treatment for Focal Atrial Tachycardia. Circulation, 2011, 123:1575-8.
- Starck, CT et al, Epicardial left atrial appendage clip occlusion also provides the electrical isolation of the left atrial appendage. Interactive Cardiovascular and Thoracic Surgery, 2012, 15(3):416-419.
- Kamohara K et al. A novel device for left atrial appendage exclusion. J Thorac Cardiovasc Surg 2005, 130(6):1639-44.
- Kamohara K et al, Evaluation of a novel device for left atrial appendage exclusion: The second-generation atrial exclusion device, J Thorac Cardiovasc Surg, 2006, 132:340-6.
- Toale C, Fitzmaurice GJ, Eaton D, Lyne J, Redmond KC. Outcomes of left atrial appendage occlusion using the AtriClip device: a systematic review. Interact CardioVasc Thorac Surg 2019; doi:10.1093/icvts/ivz156.
- Fumoto H. et al. (2008). A novel device for left atrial appendage exclusion: the third-generation atrial exclusion device. J Thorac Cardiovasc Surg, 136(4):1019-27.
- Warning: The safety and effectiveness of this device in atrial rhythm control management, either alone or in combination with ablative treatment, has not been established.
Warning: The safety and effectiveness of this device for stroke prevention, either alone or in combination with cardiac surgery, has not been established. - Emmert et al, Safe Effective and Durable Epicardial Left Atrial Appendage Clip Occlusion in Patients with AF Undergoing Cardiac Surgery: First Long-term Results from a Prospective Device Trial. European Journal of Cardio-Thoracic Surgery, 2014 Jan;45(1): 126-31.
*AtriClip PRO•V Device is not included.
