AtriClip LAA Exclusion System

97% successful left atrial appendage (LAA) exclusion1-11 resulting in the electrical isolation of the LAA 12-17

  • No Device Migrations
  • No Device Related Complications
  • With more than 5 Years Follow-up

Within minutes of the epicardial application of the AtriClip Device, the LAA becomes electrically isolated from the left atrium and ischemic injury results in the cessation of electrical activity in the LAA.12-13 Postoperatively, the excluded and necrosed LAA is resorbed and no longer a factor in the propagation of electrical activity.14-16

HALLMARKS OF ATRICLIP DEVICE EXCELLENCE


Epicardial Exclusion

  • Implant is not in the blood stream
  • Ischemic injury electrically isolates the LAA
  • Atrophy and resorption of the LAA

Constant Closing Force

  • Exclusion is maintained throughout ischemic changes to the tissue by continuous closing force.

Parallel/Linear Closing

  • Minimized occurrence of tissue folds with optimal apposition of tissue along long axis of LAA ostia

Tissue Compression/Atruamtic

  • No cutting or piercing minimizes procedure and device complications.

AtriClip Implant

Computed tomography (CT) before and at 3-year follow-up after AtriClip device implantation.  Exemplary CT before AtriClip device placement (A and C) and after implantation depicting the AtriClip device in stable position and fully excluding the left atrial appendage at a 3-year follow up (B and D).6

  1. Ailawadi et al, Exclusion of the Left Atrial Appendage with a Novel Device: Early Results of a Multicenter Trial. J Thorac Cardiovasc Surg, 2011, Nov; 142(5):1002-9, 9-8.
  2. Caliskan et al, Epicardial LAA AtriClip Occlusion Reduces the Incidence of Stroke in Patients with AF Undergoing Cardiac Surgery, Europace (2017)0, 1-10.
  3. Van Laar, Thoracoscopic Left Atrial Appendage Clipping: A Multicenter Cohort Analysis. JACC Clin Electrophysiol. 2018 4(7):893-901.
  4. Ellis et al, Angiographic Efficacy of the AtriClip Left Atrial Appendage Exclusion Device Placed by Minimally Invasive Thoracoscopic Approach, JACC Clin Electrophysiol 2017 Dec 11;3(12):1356-1365
  5. Kurfirst et al, Epicardial clip occlusion of the left atrial appendage during cardiac surgery provides optimal surgical results and long-term stability. Interact Cardiovasc Thorac Surg. 2017 25(1):37-40.
  6. Emmert et al, Safe Effective and Durable Epicardial Left Atrial Appendage Clip Occlusion in Patients with AF Undergoing Cardiac Surgery: First Long-term Results from a Prospective Device Trial.  European Journal of Cardio-Thoracic Surgery, 2014 Jan;45(1): 126-31.
  7. Ad et al, New Approach to Exclude the Left Atrial Appendage During Minimally Invasive Cryothermic Surgical Ablation. Innovations 2015; 10:323-327.
  8. Gerdisch et al, AtriClip PRO-V Left Atrial Appendage Occlusion Study, AtriCure Inc., Post Market Field Evaluation of the PRO-V Device, PM-US-0071A-1020-G.
  9. Mokracek et al, Thoracoscopic Occlusion of the Left Atrial Appendage, Innovations, vol 10, number 3, May/June 2015, 179-182.
  10. Page et al, Left Atrial Appendage Exclusion Using the AtriClip device: A Case Series, Heart Lung and Circulation, 2019 Mar;28(3):430-435.
  11. Beaver et al, Thoracoscopic Ablation with Appendage Ligation Versus Medical Therapy for Stroke Prevention: A Proof-of-Concept Randomized Trial Innovations 2016 Mar-Apr;11(2):99-105.
  12. Benussi, S. et al. (2011). Thoracoscopic Appendage Exclusion With an AtriClip Device As a Solo treatment for Focal Atrial Tachycardia. Circulation, 123:1575-8.
  13. Starck, C.T. et al. (2012). Epicardial left atrial appendage clip occlusion also provides the electrical isolation of the left atrial appendage. Interactive Cardiovascular and Thoracic Surgery, 15(3):416-9.
  14. Kamohara, K. et al. (2005). A novel device for left atrial appendage exclusion. J Thorac Cardiovasc Surg, 130(6):1639-44.
  15. Kamohara, K. et al. (2006). Evaluation of a novel device for left atrial appendage exclusion: the second-generation atrial exclusion device. J Thorac Cardiovasc Surg, 132(2):340-6.
  16. Fumoto H. et al. (2008). A novel device for left atrial appendage exclusion: the third-generation atrial exclusion device. J Thorac Cardiovasc Surg, 136(4):1019-27.
  17. Warning: The safety and effectiveness of this device in atrial rhythm control management, either alone or in combination with ablative treatment, has not been established.
    Warning: The safety and effectiveness of this device for stroke prevention, either alone or in combination with cardiac surgery, has not been established.
PM-US-1097A-0122-G